Gene name: ACS2
Reference locus (S288C): YLR153C
Gene biotype: protein_coding
Description: Acetyl-coA synthetase isoform; along with Acs1p, acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions; Belongs to the ATP-dependent AMP-binding enzyme family
Top 10 interactors (score): CIT2 (0.988); ACC1 (0.987); ACH1 (0.987); ERG10 (0.985); MLS1 (0.98); CIT3 (0.979); ACS1 (0.978); ALD6 (0.977); CIT1 (0.974); HFA1 (0.97); LAT1 (0.962); HST2 (0.96); ALD4 (0.955); ALD5 (0.955); PDB1 (0.954); POX1 (0.954); DAL7 (0.953); ALD2 (0.946); ALD3 (0.935); LEU4 (0.93)
Homologues (species, bitscore): ACSS2 (Homo sapiens, 595.9); Acss1 (Mus musculus, 604.7); acss1 (Danio rerio, 599.0); acss1 (Xenopus tropicalis, 627.5); AcCoAS (Drosophila melanogaster, 575.5); acs-19 (Caenorhabditis elegans, 499.2); ACS (Arabidopsis thaliana, 593.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:428003-430054:- | gene-YLR153C_AKU4011 | rna-NM_001182040.1_AKU4011 | cds-NP_013254.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:391774-393825:- | gene-YLR153C_BG1 | rna-NM_001182040.1_BG1 | cds-NP_013254.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:439900-441951:- | gene-YLR153C_Bruggeman | rna-NM_001182040.1_Bruggeman | cds-NP_013254.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:439284-441335:- | gene-YLR153C_CAT1 | rna-NM_001182040.1_CAT1 | cds-NP_013254.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:435146-437197:- | gene-YLR153C_CBS1585 | rna-NM_001182040.1_CBS1585 | cds-NP_013254.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:425385-427436:- | gene-YLR153C_CBS436 | rna-NM_001182040.1_CBS436 | cds-NP_013254.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:433564-435615:- | gene-YLR153C_CBS6412 | rna-NM_001182040.1_CBS6412 | cds-NP_013254.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:435411-437462:- | gene-YLR153C_CBS6413 | rna-NM_001182040.1_CBS6413 | cds-NP_013254.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:430542-432593:- | gene-YLR153C_CENPK1137D | rna-NM_001182040.1_CENPK1137D | cds-NP_013254.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:428205-430256:- | gene-YLR153C_EthanolRed | rna-NM_001182040.1_EthanolRed | cds-NP_013254.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:427714-429765:- | gene-YLR153C_FaliES1 | rna-NM_001182040.1_FaliES1 | cds-NP_013254.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000061.1:34374-36425:- | gene-YLR153C_JAY291 | rna-NM_001182040.1_JAY291 | cds-NP_013254.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:439905-441956:- | gene-YLR153C_MUCL30387 | rna-NM_001182040.1_MUCL30387 | cds-NP_013254.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:444705-446756:- | gene-YLR153C_MUCL30388 | rna-NM_001182040.1_MUCL30388 | cds-NP_013254.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:435655-437706:- | gene-YLR153C_MUCL39482 | rna-NM_001182040.1_MUCL39482 | cds-NP_013254.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:435810-437861:- | gene-YLR153C_MUCL42920 | rna-NM_001182040.1_MUCL42920 | cds-NP_013254.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:445498-447549:- | gene-YLR153C_NCIM3186 | rna-NM_001182040.1_NCIM3186 | cds-NP_013254.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:427927-429978:- | gene-YLR153C_NCYC1407 | rna-NM_001182040.1_NCYC1407 | cds-NP_013254.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:433485-435536:- | gene-YLR153C_PE2H3 | rna-NM_001182040.1_PE2H3 | cds-NP_013254.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:433226-435277:- | gene-YLR153C_PE2H4 | rna-NM_001182040.1_PE2H4 | cds-NP_013254.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:445524-447575:- | gene-YLR153C_S288C | rna-NM_001182040.1_S288C | cds-NP_013254.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:71422-73473:- | gene-YLR153C_SA1 | rna-NM_001182040.1_SA1 | cds-NP_013254.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:428926-430977:- | gene-YLR153C_ThermosaccDry | rna-NM_001182040.1_ThermosaccDry | cds-NP_013254.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:441623-443674:- | gene-YLR153C_VR1 | rna-NM_001182040.1_VR1 | cds-NP_013254.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:426709-428760:- | gene-YLR153C_ZTW1 | rna-NM_001182040.1_ZTW1 | cds-NP_013254.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:436918-438969:- | gene-YLR153C_Sparadoxus | rna-NM_001182040.1_Sparadoxus | cds-NP_013254.1_Sparadoxus | 93.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |