Gene name: ACO2
Reference locus (S288C): YJL200C
Gene biotype: protein_coding
Description: Homocitrate dehydratase, mitochondrial; Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
Top 10 interactors (score): LYS4 (0.997); IDH2 (0.995); IDH1 (0.995); CIT1 (0.988); CIT3 (0.988); CIT2 (0.983); ICL1 (0.98); FUM1 (0.978); ACO1 (0.978); LYS21 (0.956); LYS20 (0.952); LYS9 (0.945); LSC1 (0.935); KGD1 (0.933); SDH2 (0.893); YKR070W (0.881); LYS12 (0.858); MDH1 (0.857); PDB1 (0.856); KGD2 (0.853)
Homologues (species, bitscore): ACO2 (Homo sapiens, 826.2); Aco2 (Mus musculus, 824.3); aco2 (Danio rerio, 854.0); aco2 (Xenopus tropicalis, 649.0); Acon (Drosophila melanogaster, 850.1); aco-2 (Caenorhabditis elegans, 834.3); ACO3 (Arabidopsis thaliana, 210.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:44846-47215:- | gene-YJL200C_AKU4011 | rna-NM_001181633.1_AKU4011 | cds-NP_012335.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000181.1:22112-24481:- | gene-YJL200C_BG1 | rna-NM_001181633.1_BG1 | cds-NP_012335.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:56646-59015:- | gene-YJL200C_Bruggeman | rna-NM_001181633.1_Bruggeman | cds-NP_012335.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:59391-61760:- | gene-YJL200C_CAT1 | rna-NM_001181633.1_CAT1 | cds-NP_012335.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:50476-52845:- | gene-YJL200C_CBS1585 | rna-NM_001181633.1_CBS1585 | cds-NP_012335.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:75215-77584:- | gene-YJL200C_CBS436 | rna-NM_001181633.1_CBS436 | cds-NP_012335.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:46959-49328:- | gene-YJL200C_CBS6412 | rna-NM_001181633.1_CBS6412 | cds-NP_012335.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:47955-50324:- | gene-YJL200C_CBS6413 | rna-NM_001181633.1_CBS6413 | cds-NP_012335.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:38905-41274:- | gene-YJL200C_CENPK1137D | rna-NM_001181633.1_CENPK1137D | cds-NP_012335.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:49143-51512:- | gene-YJL200C_EthanolRed | rna-NM_001181633.1_EthanolRed | cds-NP_012335.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:54420-56789:- | gene-YJL200C_FaliES1 | rna-NM_001181633.1_FaliES1 | cds-NP_012335.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000301.1:45566-47935:- | gene-YJL200C_JAY291 | rna-NM_001181633.1_JAY291 | cds-NP_012335.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:58379-60748:- | gene-YJL200C_MUCL30387 | rna-NM_001181633.1_MUCL30387 | cds-NP_012335.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:54534-56903:- | gene-YJL200C_MUCL30388 | rna-NM_001181633.1_MUCL30388 | cds-NP_012335.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:49218-51587:- | gene-YJL200C_MUCL39482 | rna-NM_001181633.1_MUCL39482 | cds-NP_012335.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:53820-56189:- | gene-YJL200C_MUCL42920 | rna-NM_001181633.1_MUCL42920 | cds-NP_012335.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:56423-58792:- | gene-YJL200C_NCIM3186 | rna-NM_001181633.1_NCIM3186 | cds-NP_012335.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:47832-50201:- | gene-YJL200C_NCYC1407 | rna-NM_001181633.1_NCYC1407 | cds-NP_012335.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:60512-62881:- | gene-YJL200C_PE2H3 | rna-NM_001181633.1_PE2H3 | cds-NP_012335.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:54400-56769:- | gene-YJL200C_PE2H4 | rna-NM_001181633.1_PE2H4 | cds-NP_012335.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:56444-58813:- | gene-YJL200C_S288C | rna-NM_001181633.1_S288C | cds-NP_012335.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000022.1:95081-97450:+ | gene-YJL200C_SA1 | rna-NM_001181633.1_SA1 | cds-NP_012335.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:47615-49984:- | gene-YJL200C_ThermosaccDry | rna-NM_001181633.1_ThermosaccDry | cds-NP_012335.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:54470-56839:- | gene-YJL200C_VR1 | rna-NM_001181633.1_VR1 | cds-NP_012335.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:35193-37562:- | gene-YJL200C_ZTW1 | rna-NM_001181633.1_ZTW1 | cds-NP_012335.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:59340-61709:- | gene-YJL200C_Sparadoxus | rna-NM_001181633.1_Sparadoxus | cds-NP_012335.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |