Gene name: ACC1
Reference locus (S288C): YNR016C
Gene biotype: protein_coding
Description: Acetyl-CoA carboxylase, biotin containing enzyme; catalyzes carboxylation of cytosolic acetyl-CoA to form malonyl-CoA and regulates histone acetylation by regulating the availablity of acetyl-CoA; required for de novo biosynthesis of long-chain fatty acids; ACC1 has a paralog, HFA1, that arose from the whole genome duplication
Top 10 interactors (score): FAS1 (0.999); FAS2 (0.998); BPL1 (0.995); ACS2 (0.987); ACS1 (0.985); SNF1 (0.974); ERG10 (0.947); MCT1 (0.946); HFA1 (0.932); PYC1 (0.921); OLE1 (0.918); LAT1 (0.918); LYS21 (0.917); LYS20 (0.917); LEU4 (0.917); LEU9 (0.913); MLS1 (0.911); ACH1 (0.901); DAL7 (0.9); LSC2 (0.9)
Homologues (species, bitscore): ACACB (Homo sapiens, 1932.5); Acaca (Mus musculus, 1913.3); acaca (Danio rerio, 1951.4); acacb (Xenopus tropicalis, 1899.8); ACC (Drosophila melanogaster, 1837.0); pod-2 (Caenorhabditis elegans, 1048.5); ACC2 (Arabidopsis thaliana, 1590.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:638293-644994:- | gene-YNR016C_AKU4011 | rna-NM_001183193.1_AKU4011 | cds-NP_014413.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:546203-552904:- | gene-YNR016C_BG1 | rna-NM_001183193.1_BG1 | cds-NP_014413.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:655751-662452:- | gene-YNR016C_Bruggeman | rna-NM_001183193.1_Bruggeman | cds-NP_014413.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:689977-696678:- | gene-YNR016C_CAT1 | rna-NM_001183193.1_CAT1 | cds-NP_014413.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:644088-650789:- | gene-YNR016C_CBS1585 | rna-NM_001183193.1_CBS1585 | cds-NP_014413.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:705747-712448:- | gene-YNR016C_CBS436 | rna-NM_001183193.1_CBS436 | cds-NP_014413.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:633284-639985:- | gene-YNR016C_CBS6412 | rna-NM_001183193.1_CBS6412 | cds-NP_014413.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:634982-641683:- | gene-YNR016C_CBS6413 | rna-NM_001183193.1_CBS6413 | cds-NP_014413.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:648359-655060:- | gene-YNR016C_CENPK1137D | rna-NM_001183193.1_CENPK1137D | cds-NP_014413.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:640030-646731:- | gene-YNR016C_EthanolRed | rna-NM_001183193.1_EthanolRed | cds-NP_014413.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:631228-637929:- | gene-YNR016C_FaliES1 | rna-NM_001183193.1_FaliES1 | cds-NP_014413.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000037.1:64846-71547:+ | gene-YNR016C_JAY291 | rna-NM_001183193.1_JAY291 | cds-NP_014413.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:653495-660196:- | gene-YNR016C_MUCL30387 | rna-NM_001183193.1_MUCL30387 | cds-NP_014413.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:694338-701039:- | gene-YNR016C_MUCL30388 | rna-NM_001183193.1_MUCL30388 | cds-NP_014413.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:635593-642294:- | gene-YNR016C_MUCL39482 | rna-NM_001183193.1_MUCL39482 | cds-NP_014413.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:639745-646446:- | gene-YNR016C_MUCL42920 | rna-NM_001183193.1_MUCL42920 | cds-NP_014413.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:654642-661343:- | gene-YNR016C_NCIM3186 | rna-NM_001183193.1_NCIM3186 | cds-NP_014413.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:638099-644800:- | gene-YNR016C_NCYC1407 | rna-NM_001183193.1_NCYC1407 | cds-NP_014413.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:639156-645857:- | gene-YNR016C_PE2H3 | rna-NM_001183193.1_PE2H3 | cds-NP_014413.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:640474-647175:- | gene-YNR016C_PE2H4 | rna-NM_001183193.1_PE2H4 | cds-NP_014413.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:654673-661374:- | gene-YNR016C_S288C | rna-NM_001183193.1_S288C | cds-NP_014413.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:52382-59083:- | gene-YNR016C_SA1 | rna-NM_001183193.1_SA1 | cds-NP_014413.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:631568-638269:- | gene-YNR016C_ThermosaccDry | rna-NM_001183193.1_ThermosaccDry | cds-NP_014413.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:673499-680200:- | gene-YNR016C_VR1 | rna-NM_001183193.1_VR1 | cds-NP_014413.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:540979-547680:- | gene-YNR016C_ZTW1 | rna-NM_001183193.1_ZTW1 | cds-NP_014413.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:645670-652371:- | gene-YNR016C_Sparadoxus | rna-NM_001183193.1_Sparadoxus | cds-NP_014413.1_Sparadoxus | 93.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |