ACA1 (YER045C)


Gene profile

Gene name: ACA1
Reference locus (S288C): YER045C
Gene biotype: protein_coding

Description: ATF/CREB activator 1; ATF/CREB family basic leucine zipper (bZIP) transcription factor; binds as a homodimer to the ATF/CREB consensus sequence TGACGTCA; important for carbon source utilization; target genes include GRE2 and COS8; ACA1 has a paralog, CST6, that arose from the whole genome duplication

Top 10 interactors (score): GCN4 (0.996); SKO1 (0.971); HOG1 (0.968); SLT2 (0.957); FUS3 (0.957); SMK1 (0.956); KSS1 (0.956); HTB2 (0.901); HTB1 (0.901); RLF2 (0.764); SRV2 (0.76); CYR1 (0.699); SUT1 (0.693); SKN7 (0.664); YAP1 (0.636); ADR1 (0.614); NRG1 (0.613); BAS1 (0.582); KDX1 (0.578); YPR196W (0.572)

Homologues (species, bitscore): FOS (Homo sapiens, 50.1); atf2 (Danio rerio, 50.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:234090-235559:- gene-YER045C_AKU4011 rna-NM_001178936.3_AKU4011 cds-NP_010964.3_AKU4011 98.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:190152-191621:+ gene-YER045C_BG1 rna-NM_001178936.3_BG1 cds-NP_010964.3_BG1 98.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:242948-244417:- gene-YER045C_Bruggeman rna-NM_001178936.3_Bruggeman cds-NP_010964.3_Bruggeman 98.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:237060-238529:- gene-YER045C_CAT1 rna-NM_001178936.3_CAT1 cds-NP_010964.3_CAT1 98.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:233999-235468:- gene-YER045C_CBS1585 rna-NM_001178936.3_CBS1585 cds-NP_010964.3_CBS1585 98.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:235948-237417:- gene-YER045C_CBS436 rna-NM_001178936.3_CBS436 cds-NP_010964.3_CBS436 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:233860-235329:- gene-YER045C_CBS6412 rna-NM_001178936.3_CBS6412 cds-NP_010964.3_CBS6412 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:239470-240939:- gene-YER045C_CBS6413 rna-NM_001178936.3_CBS6413 cds-NP_010964.3_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:238225-239694:- gene-YER045C_CENPK1137D rna-NM_001178936.3_CENPK1137D cds-NP_010964.3_CENPK1137D 98.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:234694-236163:- gene-YER045C_EthanolRed rna-NM_001178936.3_EthanolRed cds-NP_010964.3_EthanolRed 98.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:234957-236426:- gene-YER045C_FaliES1 rna-NM_001178936.3_FaliES1 cds-NP_010964.3_FaliES1 98.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000192.1:32724-34193:- gene-YER045C_JAY291 rna-NM_001178936.3_JAY291 cds-NP_010964.3_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:238399-239868:- gene-YER045C_MUCL30387 rna-NM_001178936.3_MUCL30387 cds-NP_010964.3_MUCL30387 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:234614-236083:- gene-YER045C_MUCL30388 rna-NM_001178936.3_MUCL30388 cds-NP_010964.3_MUCL30388 98.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:233041-234510:- gene-YER045C_MUCL39482 rna-NM_001178936.3_MUCL39482 cds-NP_010964.3_MUCL39482 98.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:240117-241586:- gene-YER045C_MUCL42920 rna-NM_001178936.3_MUCL42920 cds-NP_010964.3_MUCL42920 98.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:240031-241500:- gene-YER045C_NCIM3186 rna-NM_001178936.3_NCIM3186 cds-NP_010964.3_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:238103-239572:- gene-YER045C_NCYC1407 rna-NM_001178936.3_NCYC1407 cds-NP_010964.3_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:248737-250206:- gene-YER045C_PE2H3 rna-NM_001178936.3_PE2H3 cds-NP_010964.3_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:238678-240147:- gene-YER045C_PE2H4 rna-NM_001178936.3_PE2H4 cds-NP_010964.3_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:240032-241501:- gene-YER045C_S288C rna-NM_001178936.3_S288C cds-NP_010964.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:2186-3655:+ gene-YER045C_SA1 rna-NM_001178936.3_SA1 cds-NP_010964.3_SA1 98.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:235729-237198:- gene-YER045C_ThermosaccDry rna-NM_001178936.3_ThermosaccDry cds-NP_010964.3_ThermosaccDry 98.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:234833-236302:- gene-YER045C_VR1 rna-NM_001178936.3_VR1 cds-NP_010964.3_VR1 99.0 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:232939-234408:- gene-YER045C_ZTW1 rna-NM_001178936.3_ZTW1 cds-NP_010964.3_ZTW1 98.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:236776-238254:- gene-YER045C_Sparadoxus rna-NM_001178936.3_Sparadoxus cds-NP_010964.3_Sparadoxus 82.7 99.3 Verified 1 1 1 False True False False False

Additional files