Gene name: ABP140
Reference locus (S288C): YOR239W
Gene biotype: protein_coding
Description: tRNA(Thr) (cytosine(32)-N(3))-methyltransferase; AdoMet-dependent tRNA methyltransferase and actin binding protein; C-terminal domain is responsible for 3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA-Thr and tRNA-Ser and contains an S-adenosylmethionine (AdoMet) binding motif; N-terminal actin binding sequence interacts with actin filaments and localizes to actin patches and cables; N- and C-terminal domains are encoded in separate ORFs that are translated into one protein via a +1 frameshift; Belongs to the methyltransferase superfamily. METL family
Top 10 interactors (score): ACT1 (0.971); SAC6 (0.953); FCF2 (0.895); MRT4 (0.894); SES1 (0.885); NOC4 (0.876); EST3 (0.866); ABP1 (0.862); NIP7 (0.856); BNR1 (0.853); ATS1 (0.819); TRM3 (0.811); CBF5 (0.791); DIA4 (0.778); TRM1 (0.774); BNI1 (0.773); NCL1 (0.772); ARP2 (0.771); TRM11 (0.771); COF1 (0.766)
Homologues (species, bitscore): METTL2B (Homo sapiens, 240.4); Mettl2 (Mus musculus, 252.7); mettl2a (Danio rerio, 255.8); mettl2b (Xenopus tropicalis, 257.7); metl (Drosophila melanogaster, 250.4); metl-2 (Caenorhabditis elegans, 246.1); AT2G26200 (Arabidopsis thaliana, 191.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:775630-777517:+ | gene-YOR239W_AKU4011 | rna-NM_001183658.6_AKU4011 | cds-NP_014882.4_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:177669-179556:+ | gene-YOR239W_BG1 | rna-NM_001183658.6_BG1 | cds-NP_014882.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:761096-762983:+ | gene-YOR239W_Bruggeman | rna-NM_001183658.6_Bruggeman | cds-NP_014882.4_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:761746-763633:+ | gene-YOR239W_CAT1 | rna-NM_001183658.6_CAT1 | cds-NP_014882.4_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:758619-760506:+ | gene-YOR239W_CBS1585 | rna-NM_001183658.6_CBS1585 | cds-NP_014882.4_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:757313-759200:+ | gene-YOR239W_CBS436 | rna-NM_001183658.6_CBS436 | cds-NP_014882.4_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:755738-757625:+ | gene-YOR239W_CBS6412 | rna-NM_001183658.6_CBS6412 | cds-NP_014882.4_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:764378-766265:+ | gene-YOR239W_CBS6413 | rna-NM_001183658.6_CBS6413 | cds-NP_014882.4_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:784621-786507:+ | gene-YOR239W_CENPK1137D | rna-NM_001183658.6_CENPK1137D | cds-NP_014882.4_CENPK1137D | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:751750-753637:+ | gene-YOR239W_EthanolRed | rna-NM_001183658.6_EthanolRed | cds-NP_014882.4_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:757149-759036:+ | gene-YOR239W_FaliES1 | rna-NM_001183658.6_FaliES1 | cds-NP_014882.4_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:67803-69690:- | gene-YOR239W_JAY291 | rna-NM_001183658.6_JAY291 | cds-NP_014882.4_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:765367-767254:+ | gene-YOR239W_MUCL30387 | rna-NM_001183658.6_MUCL30387 | cds-NP_014882.4_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:772485-774372:+ | gene-YOR239W_MUCL30388 | rna-NM_001183658.6_MUCL30388 | cds-NP_014882.4_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:765949-767836:+ | gene-YOR239W_MUCL39482 | rna-NM_001183658.6_MUCL39482 | cds-NP_014882.4_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:775537-777424:+ | gene-YOR239W_MUCL42920 | rna-NM_001183658.6_MUCL42920 | cds-NP_014882.4_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:784746-786633:+ | gene-YOR239W_NCIM3186 | rna-NM_001183658.6_NCIM3186 | cds-NP_014882.4_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:766048-767935:+ | gene-YOR239W_NCYC1407 | rna-NM_001183658.6_NCYC1407 | cds-NP_014882.4_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:765349-767236:+ | gene-YOR239W_PE2H3 | rna-NM_001183658.6_PE2H3 | cds-NP_014882.4_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:775726-777613:+ | gene-YOR239W_PE2H4 | rna-NM_001183658.6_PE2H4 | cds-NP_014882.4_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:784857-786744:+ | gene-YOR239W_S288C | rna-NM_001183658.6_S288C | cds-NP_014882.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:194850-196737:+ | gene-YOR239W_SA1 | rna-NM_001183658.6_SA1 | cds-NP_014882.4_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:756332-758219:+ | gene-YOR239W_ThermosaccDry | rna-NM_001183658.6_ThermosaccDry | cds-NP_014882.4_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:819789-821676:+ | gene-YOR239W_VR1 | rna-NM_001183658.6_VR1 | cds-NP_014882.4_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:489249-491135:+ | gene-YOR239W_ZTW1 | rna-NM_001183658.6_ZTW1 | cds-NP_014882.4_ZTW1 | 99.2 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:762243-764130:+ | gene-YOR239W_Sparadoxus | rna-NM_001183658.6_Sparadoxus | cds-NP_014882.4_Sparadoxus | 87.3 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |