ABP1 (YCR088W)


Gene profile

Gene name: ABP1
Reference locus (S288C): YCR088W
Gene biotype: protein_coding

Description: Actin-binding protein of the cortical actin cytoskeleton; important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; inhibits barbed-end actin filament elongation; phosphorylation within its Proline-Rich Regio, mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa)

Top 10 interactors (score): ACT1 (0.999); SLA2 (0.999); ARP2 (0.999); PRK1 (0.997); CAP2 (0.997); ARK1 (0.995); SAC6 (0.992); LAS17 (0.99); SRV2 (0.99); SLA1 (0.99); RVS167 (0.989); ARP3 (0.987); PAN1 (0.981); BZZ1 (0.978); EDE1 (0.973); MYO5 (0.97); COF1 (0.968); VRP1 (0.966); SCP1 (0.964); ARC35 (0.962)

Homologues (species, bitscore): DBNL (Homo sapiens, 65.5); Dbnl (Mus musculus, 68.2); dbnlb (Danio rerio, 89.7); hcls1 (Xenopus tropicalis, 64.7); Abp1 (Drosophila melanogaster, 73.2); F42H10.3 (Caenorhabditis elegans, 56.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:259559-261337:+ gene-YCR088W_AKU4011 rna-NM_001178794.1_AKU4011 cds-NP_010012.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000067.1:118310-120088:+ gene-YCR088W_BG1 rna-NM_001178794.1_BG1 cds-NP_010012.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:255750-257528:+ gene-YCR088W_Bruggeman rna-NM_001178794.1_Bruggeman cds-NP_010012.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:266815-268593:+ gene-YCR088W_CAT1 rna-NM_001178794.1_CAT1 cds-NP_010012.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:254373-256151:+ gene-YCR088W_CBS1585 rna-NM_001178794.1_CBS1585 cds-NP_010012.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:266147-267925:+ gene-YCR088W_CBS436 rna-NM_001178794.1_CBS436 cds-NP_010012.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:245726-247504:+ gene-YCR088W_CBS6412 rna-NM_001178794.1_CBS6412 cds-NP_010012.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:260424-262202:+ gene-YCR088W_CBS6413 rna-NM_001178794.1_CBS6413 cds-NP_010012.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:264451-266229:+ gene-YCR088W_CENPK1137D rna-NM_001178794.1_CENPK1137D cds-NP_010012.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:255386-257164:+ gene-YCR088W_EthanolRed rna-NM_001178794.1_EthanolRed cds-NP_010012.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:260749-262527:+ gene-YCR088W_FaliES1 rna-NM_001178794.1_FaliES1 cds-NP_010012.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000323.1:26279-28057:- gene-YCR088W_JAY291 rna-NM_001178794.1_JAY291 cds-NP_010012.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:252879-254657:+ gene-YCR088W_MUCL30387 rna-NM_001178794.1_MUCL30387 cds-NP_010012.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:252757-254535:+ gene-YCR088W_MUCL30388 rna-NM_001178794.1_MUCL30388 cds-NP_010012.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:260937-262715:+ gene-YCR088W_MUCL39482 rna-NM_001178794.1_MUCL39482 cds-NP_010012.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:257604-259382:+ gene-YCR088W_MUCL42920 rna-NM_001178794.1_MUCL42920 cds-NP_010012.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:264700-266478:+ gene-YCR088W_NCIM3186 rna-NM_001178794.1_NCIM3186 cds-NP_010012.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:261777-263555:+ gene-YCR088W_NCYC1407 rna-NM_001178794.1_NCYC1407 cds-NP_010012.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:276328-278106:+ gene-YCR088W_PE2H3 rna-NM_001178794.1_PE2H3 cds-NP_010012.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:264880-266658:+ gene-YCR088W_PE2H4 rna-NM_001178794.1_PE2H4 cds-NP_010012.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:265068-266846:+ gene-YCR088W_S288C rna-NM_001178794.1_S288C cds-NP_010012.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000044.1:64900-66678:+ gene-YCR088W_SA1 rna-NM_001178794.1_SA1 cds-NP_010012.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:260676-262454:+ gene-YCR088W_ThermosaccDry rna-NM_001178794.1_ThermosaccDry cds-NP_010012.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:271869-273647:+ gene-YCR088W_VR1 rna-NM_001178794.1_VR1 cds-NP_010012.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:258517-260295:+ gene-YCR088W_ZTW1 rna-NM_001178794.1_ZTW1 cds-NP_010012.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:292631-294406:+ gene-YCR088W_Sparadoxus rna-NM_001178794.1_Sparadoxus cds-NP_010012.1_Sparadoxus 90.2 99.8 Verified 1 1 1 False True False False False

Additional files