ABF2 (YMR072W)


Gene profile

Gene name: ABF2
Reference locus (S288C): YMR072W
Gene biotype: protein_coding

Description: ARS-binding factor 2, mitochondrial; Mitochondrial DNA-binding protein; involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation; ABF2 has a paralog, IXR1, that arose from the whole genome duplication; human homolog TFAM can complement yeast abf2 mutant, rescuing the loss-of-mitochondrial DNA phenotype in a yeast abf2 strain

Top 10 interactors (score): RPO41 (0.881); NHP6A (0.87); NHP10 (0.845); CCE1 (0.84); HMO1 (0.836); ILV5 (0.834); ACO1 (0.828); MGM101 (0.813); HTA2 (0.796); MHR1 (0.776); ORI5 (0.771); CMR1 (0.761); NHP6B (0.753); HTA1 (0.715); MCX1 (0.713); MMM1 (0.712); CHD1 (0.704); PIF1 (0.699); HTB1 (0.671); SPT16 (0.666)

Homologues (species, bitscore): HMGB3 (Homo sapiens, 58.5); Hmgb3 (Mus musculus, 56.2); ssrp1a (Danio rerio, 59.3); ssrp1 (Xenopus tropicalis, 56.6); HmgZ (Drosophila melanogaster, 52.8); HMGB2 (Arabidopsis thaliana, 59.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:449274-449825:+ gene-YMR072W_AKU4011 rna-NM_001182570.1_AKU4011 cds-NP_013788.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:92959-93510:- gene-YMR072W_BG1 rna-NM_001182570.1_BG1 cds-NP_013788.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:391425-391976:+ gene-YMR072W_Bruggeman rna-NM_001182570.1_Bruggeman cds-NP_013788.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:391788-392339:+ gene-YMR072W_CAT1 rna-NM_001182570.1_CAT1 cds-NP_013788.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:382217-382768:+ gene-YMR072W_CBS1585 rna-NM_001182570.1_CBS1585 cds-NP_013788.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:387770-388321:+ gene-YMR072W_CBS436 rna-NM_001182570.1_CBS436 cds-NP_013788.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:495290-495841:+ gene-YMR072W_CBS6412 rna-NM_001182570.1_CBS6412 cds-NP_013788.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:381474-382025:+ gene-YMR072W_CBS6413 rna-NM_001182570.1_CBS6413 cds-NP_013788.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:405674-406225:+ gene-YMR072W_CENPK1137D rna-NM_001182570.1_CENPK1137D cds-NP_013788.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:382079-382630:+ gene-YMR072W_EthanolRed rna-NM_001182570.1_EthanolRed cds-NP_013788.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:385245-385796:+ gene-YMR072W_FaliES1 rna-NM_001182570.1_FaliES1 cds-NP_013788.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:51160-51711:- gene-YMR072W_JAY291 rna-NM_001182570.1_JAY291 cds-NP_013788.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:387157-387708:+ gene-YMR072W_MUCL30387 rna-NM_001182570.1_MUCL30387 cds-NP_013788.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:391845-392396:+ gene-YMR072W_MUCL30388 rna-NM_001182570.1_MUCL30388 cds-NP_013788.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:382505-383056:+ gene-YMR072W_MUCL39482 rna-NM_001182570.1_MUCL39482 cds-NP_013788.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:389158-389709:+ gene-YMR072W_MUCL42920 rna-NM_001182570.1_MUCL42920 cds-NP_013788.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:411523-412074:+ gene-YMR072W_NCIM3186 rna-NM_001182570.1_NCIM3186 cds-NP_013788.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:382417-382968:+ gene-YMR072W_NCYC1407 rna-NM_001182570.1_NCYC1407 cds-NP_013788.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:388368-388919:+ gene-YMR072W_PE2H3 rna-NM_001182570.1_PE2H3 cds-NP_013788.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:394463-395014:+ gene-YMR072W_PE2H4 rna-NM_001182570.1_PE2H4 cds-NP_013788.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:411569-412120:+ gene-YMR072W_S288C rna-NM_001182570.1_S288C cds-NP_013788.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:138050-138601:- gene-YMR072W_SA1 rna-NM_001182570.1_SA1 cds-NP_013788.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:383048-383599:+ gene-YMR072W_ThermosaccDry rna-NM_001182570.1_ThermosaccDry cds-NP_013788.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:394952-395503:+ gene-YMR072W_VR1 rna-NM_001182570.1_VR1 cds-NP_013788.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:361322-361873:+ gene-YMR072W_ZTW1 rna-NM_001182570.1_ZTW1 cds-NP_013788.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:394884-395436:+ gene-YMR072W_Sparadoxus rna-NM_001182570.1_Sparadoxus cds-NP_013788.1_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files