Gene name: AAD4
Reference locus (S288C): YDL243C
Gene biotype: protein_coding
Description: Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; expression induced in cells treated with the mycotoxin patulin; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family
Top 10 interactors (score): AAD16 (0.923); AAD6 (0.907); OYE3 (0.797); YKL071W (0.784); AAD14 (0.781); YCR102C (0.775); YKL070W (0.755); ADH7 (0.718); BDH2 (0.705); YDL247W-A (0.7); CIS1 (0.697); YAL056C-A (0.695); YAL059C-A (0.695); COS7 (0.695); YLL056C (0.669); PBR1 (0.664); PAU8 (0.651); ECM4 (0.632); SEC4 (0.623); GRE2 (0.601)
Homologues (species, bitscore): AKR7A3 (Homo sapiens, 90.9); Akr7a5 (Mus musculus, 85.9); akr7a3 (Danio rerio, 71.6); akr7a2 (Xenopus tropicalis, 76.6); AT1G60680 (Arabidopsis thaliana, 129.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:749-1738:- | gene-YDL243C_AKU4011 | rna-NM_001180303.1_AKU4011 | cds-NP_010038.1_AKU4011 | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000085.1:1619-2696:- | gene-YDL243C_BG1 | rna-NM_001180303.1_BG1 | cds-NP_010038.1_BG1 | 81.3 | 99.3 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:8807-9796:- | gene-YDL243C_Bruggeman | rna-NM_001180303.1_Bruggeman | cds-NP_010038.1_Bruggeman | 92.4 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:15893-16882:- | gene-YDL243C_CAT1 | rna-NM_001180303.1_CAT1 | cds-NP_010038.1_CAT1 | 95.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:117-1106:- | gene-YDL243C_CBS1585 | rna-NM_001180303.1_CBS1585 | cds-NP_010038.1_CBS1585 | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:16829-17818:- | gene-YDL243C_CBS436 | rna-NM_001180303.1_CBS436 | cds-NP_010038.1_CBS436 | 95.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:565-1554:- | gene-YDL243C_CBS6412 | rna-NM_001180303.1_CBS6412 | cds-NP_010038.1_CBS6412 | 93.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:17505-18494:- | gene-YDL243C_CBS6413 | rna-NM_001180303.1_CBS6413 | cds-NP_010038.1_CBS6413 | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:16544-17533:- | gene-YDL243C_CENPK1137D | rna-NM_001180303.1_CENPK1137D | cds-NP_010038.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:14284-15280:- | gene-YDL243C_EthanolRed | rna-NM_001180303.1_EthanolRed | cds-NP_010038.1_EthanolRed | 93.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:17586-18582:- | gene-YDL243C_FaliES1 | rna-NM_001180303.1_FaliES1 | cds-NP_010038.1_FaliES1 | 93.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:590-1579:- | gene-YDL243C_JAY291 | rna-NM_001180303.1_JAY291 | cds-NP_010038.1_JAY291 | 88.8 | 99.1 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:15710-16699:- | gene-YDL243C_MUCL30387 | rna-NM_001180303.1_MUCL30387 | cds-NP_010038.1_MUCL30387 | 92.4 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:5277-6266:- | gene-YDL243C_MUCL30388 | rna-NM_001180303.1_MUCL30388 | cds-NP_010038.1_MUCL30388 | 92.4 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:712-1701:- | gene-YDL243C_MUCL39482 | rna-NM_001180303.1_MUCL39482 | cds-NP_010038.1_MUCL39482 | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:15662-16651:- | gene-YDL243C_MUCL42920 | rna-NM_001180303.1_MUCL42920 | cds-NP_010038.1_MUCL42920 | 92.4 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:17500-18489:- | gene-YDL243C_NCIM3186 | rna-NM_001180303.1_NCIM3186 | cds-NP_010038.1_NCIM3186 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:669-1658:- | gene-YDL243C_NCYC1407 | rna-NM_001180303.1_NCYC1407 | cds-NP_010038.1_NCYC1407 | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:11470-12459:- | gene-YDL243C_PE2H3 | rna-NM_001180303.1_PE2H3 | cds-NP_010038.1_PE2H3 | 88.8 | 99.1 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:11021-12010:- | gene-YDL243C_PE2H4 | rna-NM_001180303.1_PE2H4 | cds-NP_010038.1_PE2H4 | 88.8 | 99.1 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:17577-18566:- | gene-YDL243C_S288C | rna-NM_001180303.1_S288C | cds-NP_010038.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000107.1:25732-26715:+ | gene-YDL243C_SA1 | rna-NM_001180303.1_SA1 | cds-NP_010038.1_SA1 | 92.6 | 99.3 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:17714-18710:- | gene-YDL243C_ThermosaccDry | rna-NM_001180303.1_ThermosaccDry | cds-NP_010038.1_ThermosaccDry | 93.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:17649-18632:- | gene-YDL243C_VR1 | rna-NM_001180303.1_VR1 | cds-NP_010038.1_VR1 | 92.6 | 99.3 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:16786-17775:- | gene-YDL243C_ZTW1 | rna-NM_001180303.1_ZTW1 | cds-NP_010038.1_ZTW1 | 92.9 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |