Gene name: AAD3
Reference locus (S288C): YCR107W
Gene biotype: protein_coding
Description: Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; AAD3 has a paralog, AAD15, that arose from a segmental duplication; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily
Top 10 interactors (score): AAD15 (0.874); ADH7 (0.778); YOL166W-A (0.711); PAU3 (0.696); YMR320W (0.694); YHR214W-A (0.693); YOR381W-A (0.673); SEC4 (0.623); YOR385W (0.619); PAU15 (0.614); SAM4 (0.574); RDS1 (0.563); YAR068W (0.555); ALD3 (0.507); ALD2 (0.462); PET8 (0.454); FRE5 (0.453); AKR2 (0.451); ARO10 (0.45); YOR387C (0.45)
Homologues (species, bitscore): AKR7A3 (Homo sapiens, 85.5); Akr7a5 (Mus musculus, 81.3); akr7a3 (Danio rerio, 67.0); akr7a2 (Xenopus tropicalis, 75.1); AT1G60690 (Arabidopsis thaliana, 108.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000028.1:443-1517:+ | gene-YCR107W_BG1 | rna-NM_001178814.1_BG1 | cds-NP_010032.1_BG1 | 98.2 | 98.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:307165-308256:+ | gene-YCR107W_Bruggeman | rna-NM_001178814.1_Bruggeman | cds-NP_010032.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:317509-318600:+ | gene-YCR107W_CAT1 | rna-NM_001178814.1_CAT1 | cds-NP_010032.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:316442-317533:+ | gene-YCR107W_CBS436 | rna-NM_001178814.1_CBS436 | cds-NP_010032.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:10670-11749:- | gene-YCR107W_CENPK1137D | rna-NM_001178814.1_CENPK1137D | cds-NP_010032.1_CENPK1137D | 83.0 | 98.0 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:15455-16547:- | gene-YCR107W_EthanolRed | rna-NM_001178814.1_EthanolRed | cds-NP_010032.1_EthanolRed | 93.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:15404-16496:- | gene-YCR107W_FaliES1 | rna-NM_001178814.1_FaliES1 | cds-NP_010032.1_FaliES1 | 93.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:303720-304811:+ | gene-YCR107W_MUCL30387 | rna-NM_001178814.1_MUCL30387 | cds-NP_010032.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:302219-303310:+ | gene-YCR107W_MUCL30388 | rna-NM_001178814.1_MUCL30388 | cds-NP_010032.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000138.1:1-983:- | gene-YCR107W_MUCL42920 | rna-NM_001178814.1_MUCL42920 | cds-NP_010032.1_MUCL42920 | 72.7 | 88.6 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:683207-684286:+ | gene-YCR107W_PE2H3 | rna-NM_001178814.1_PE2H3 | cds-NP_010032.1_PE2H3 | 90.6 | 98.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:319766-320857:+ | gene-YCR107W_PE2H4 | rna-NM_001178814.1_PE2H4 | cds-NP_010032.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:313890-314981:+ | gene-YCR107W_S288C | rna-NM_001178814.1_S288C | cds-NP_010032.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000132.1:1-582:- | gene-YCR107W_SA1 | rna-NM_001178814.1_SA1 | cds-NP_010032.1_SA1 | 53.2 | 53.2 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:15393-16485:- | gene-YCR107W_ThermosaccDry | rna-NM_001178814.1_ThermosaccDry | cds-NP_010032.1_ThermosaccDry | 93.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:326654-327745:+ | gene-YCR107W_VR1 | rna-NM_001178814.1_VR1 | cds-NP_010032.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000005.1:3768-4860:- | gene-YCR107W_ZTW1 | rna-NM_001178814.1_ZTW1 | cds-NP_010032.1_ZTW1 | 93.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:722383-723473:+ | gene-YCR107W_Sparadoxus | rna-NM_001178814.1_Sparadoxus | cds-NP_010032.1_Sparadoxus | 76.7 | 97.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |